46 days in Panama Itinerary

46 days in Panama Itinerary

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Route & dates

46 days in Panama Itinerary

Start: Denver
Fly + Drive:  11​h 30​min
1
Portobelo
— 3 nights
Drive:  1​h 15​min
2
Colon
— 5 nights
Drive:  2​h 45​min
3
El Valle de Anton
— 5 nights
bus + Fly:  3​h 30​min
4
Bocas Town, Isla Colon
— 5 nights
Drive:  4​h 45​min
5
Boquete
— 7 nights
Drive:  2​h
6
Cerro Punta
— 2 nights
bus:  5​h 30​min
7
Isla de Coiba
— 1 night
+2
Fly + taxi + ferry:  5​h 15​min
8
Isla Taboga
— 1 night
Drive:  1​h 30​min
9
Panama City
— 10 nights
ferry:  1​h
10
Contadora Island
— 2 nights
+2
ferry + bus + Fly:  4​h 15​min
11
Darien Province
— 1 night
Fly:  3​h
12
San Blas Islands
— 3 nights
Drive + Fly:  12​h
End: Denver

3
nights
Portobelo

The ruins of a Spanish colonial port city dot the landscape of the Caribbean fishing village of Portobelo, a reminder that this humble and relaxed place was once integral to the workings of an empire.
Portobelo is known for wildlife, zoos & aquariums, museums, and beaches. Your plan includes some of its best attractions: discover the deep blue sea with a scuba or snorkeling tour, get interesting insight from Tours, tour the pleasant surroundings at Playa Blanca, and appreciate the history behind Black Christ.

To see photos, other places to visit, and other tourist information, you can read our Portobelo itinerary planning website .

Denver, USA to Portobelo is an approximately 11.5-hour combination of flight and car. You'll lose 2 hours traveling from Denver to Portobelo due to the time zone difference. On the 18th (Tue), wrap the sightseeing up by early afternoon so you can drive to Colon.

Things to do in Portobelo

Outdoors Wildlife Parks
Find places to stay Feb 15 — 18:
Highlights from your plan
Scuba & Snorkeling
Museo de La Real Aduana de Portobelo ©
Nature & Wildlife Tours

5
nights
Colon

Colon ©
Founded in the 1850s by Americans building the country's first railroad, Colon is now one of the largest duty-free ports in the world.
Change things up with a short trip to Nature & Wildlife Tours in Gamboa (about 1h 10 min away). Spend the 23rd (Sun) exploring nature at Portobelo National Park. There's much more to do: make a trip to Gatun Locks, enjoy breathtaking views from Observation Centre Canal Expansion, gain insight at The Galeta Marine Laboratory, and take in the architecture and atmosphere at Catedral Inmaculada Concepcion.

To find more things to do, traveler tips, other places to visit, and more tourist information, you can read our Colon attractions planning website .

You can drive from Portobelo to Colon in 1.5 hours. Another option is to take a bus. Wrap up your sightseeing on the 23rd (Sun) early enough to drive to El Valle de Anton.

Things to do in Colon

Historic Sites Nature Parks

Side Trip

Nature & Wildlife Tours
Find places to stay Feb 18 — 23:
Highlights from your plan
Fort San Lorenzo ©
Fort San Lorenzo
Gatun Locks
Gatun Locks
Panamá-Canal Railroad ©
Panamá-Canal Railroad

5
nights
El Valle de Anton

El Valle de Anton ©
Surrounded by lush forests and spectacular mountains, El Valle de Anton serves as the perfect spot to enjoy some of Panama's finest natural attractions.
Get out of town with these interesting El Valle de Anton side-trips: Leading Adventures (in Rio Hato), Playa Santa Clara (in Penonome) and Farallon Butterflies (in Farallon). There's much more to do: learn about wildlife with up-close encounters at El Nispero Zoo and Botanical Garden, witness a stunning natural landmark at Los Pozos Termales, walk around Ecoparque Don Arcelio, and identify plant and animal life at Butterfly Haven.

To see traveler tips, reviews, photos, and other tourist information, refer to the El Valle de Anton route planner .

You can drive from Colon to El Valle de Anton in 3 hours. Alternatively, you can take a bus. Finish up your sightseeing early on the 28th (Fri) so you can travel to Bocas Town.

Things to do in El Valle de Anton

Parks Nature Wildlife

Side Trips

Nata, Farallon Butterflies, Playa Santa Clara, Leading Adventures
Find places to stay Feb 23 — 28:
Highlights from your plan
El Nispero Zoo and Botanical Garden ©
Butterfly Haven
Butterfly Haven
The Sleeping Indian Girl ©
The Sleeping Indian Girl

5
nights
Bocas Town, Isla Colon

The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.
When in Bocas Town, make a side trip to see Playa Bluff in Bluff Beach, approximately 30 minutes away. Next up on the itinerary: discover the deep blue sea with a scuba or snorkeling tour, explore the engaging exhibits at Plastic Bottle Village, enjoy the sand and surf at Starfish Beach, and stroll around Parque Nacional Marino Isla Bastimentos.

For where to stay, reviews, photos, and more tourist information, use the Bocas Town journey planner .

You can do a combination of bus and flight from El Valle de Anton to Bocas Town in 3.5 hours. Alternatively, you can do a combination of taxi and flight; or do a combination of bus and ferry. In February, daily temperatures in Bocas Town can reach 80°F, while at night they dip to 80°F. Finish your sightseeing early on the 4th (Wed) to allow enough time to drive to Boquete.

Things to do in Bocas Town

Parks Outdoors Beaches

Side Trips

Playa Bluff, Finca Los Monos Botanical Garden, Up In The Hill
Find places to stay Feb 28 — Mar 4:
Highlights from your plan
Scuba & Snorkeling
Finca Los Monos Botanical Garden ©
Finca Los Monos Botanical Garden
Boca del Drago ©
Boca del Drago

7
nights
Boquete

Boquete ©
Now known internationally for its fresh mountain air, year-round pleasant temperatures, and large community of North American expats, Boquete has changed rapidly since the start of the century, changing from a humble mountain town, into a humble mountain surrounded by gated communities and estates.
Boquete is known for nature, spas, trails, breweries & distilleries, and wildlife. Your plan includes some of its best attractions: savor the flavors at Food & Drink, take a pleasant ride with a tour on horseback, get lost in a book at Biblioteca de Boquete, and explore the wealth of natural beauty at Volcan Baru National Park.

For other places to visit, traveler tips, ratings, and more tourist information, refer to the Boquete holiday planner .

Traveling by car from Bocas Town to Boquete takes 5 hours. Wrap up your sightseeing on the 11th (Wed) early enough to drive to Cerro Punta.

Things to do in Boquete

Parks Nature Outdoors

Side Trip

Bocas del Toro Province
Find places to stay Mar 4 — 11:
Highlights from your plan
Volcan Baru National Park ©
Volcan Baru National Park
Coffee & Tea Tours

2
nights
Cerro Punta

Cerro Punta ©
Cerro Punta is a city and corregimiento in Tierras Altas District, Chiriquí Province, Panama. On the 12th (Thu), wander the wide-open spaces of Haras Cerro Punta, admire the natural beauty at Finca Dracula, and then stroll through Quetzal Trail. On your second day here, make a trip to Arte Cruz, see the interesting displays at Sitio Barriles Museum, then get to know the resident critters at Raquel's Ark, and finally relax in the rural setting at Lagunas Adventures on The Janson Coffee Farm.

For traveler tips, maps, where to stay, and tourist information, go to the Cerro Punta trip itinerary maker .

Getting from Boquete to Cerro Punta by car takes about 2 hours. Other options: take a bus. Finish your sightseeing early on the 13th (Fri) to allow enough time to take a bus to Isla de Coiba.

Things to do in Cerro Punta

Parks Trails Outdoors

Side Trips

Volcan, Quetzal Trail
Find places to stay Mar 11 — 13:
Highlights from your plan
Finca Dracula ©
Finca Dracula
Sitio Barriles Museum ©
Sitio Barriles Museum
Haras Cerro Punta ©
Haras Cerro Punta

1
night
Isla de Coiba

Isla de Coiba ©
Kick off your visit on the 14th (Sat): explore the striking landscape of Parque Nacional de Isla Coiba.

For reviews, ratings, other places to visit, and tourist information, go to the Isla de Coiba attractions planner.

Traveling by bus from Cerro Punta to Isla de Coiba takes 5.5 hours. Wrap up your sightseeing on the 14th (Sat) to allow time to travel to Isla Taboga.

Things to do in Isla de Coiba

Nature Wildlife Parks
Find places to stay Mar 13 — 14:
Highlights from your plan
Parque Nacional de Isla Coiba ©
Parque Nacional de Isla Coiba

1
night
Isla Taboga

Isla Taboga ©
Less than an hour's boat ride from the capital, Isla Taboga offers a picturesque retreat from the commercialism and bustle of Panama City.
Kick off your visit on the 15th (Sun): don't miss a visit to Iglesia de San Pedro and then step off the mainland to explore Taboga Island Beaches.

For traveler tips, photos, and tourist information, refer to the Isla Taboga trip maker website .

Traveling by combination of flight and ferry from Isla de Coiba to Isla Taboga takes 5.5 hours. Alternatively, you can do a combination of bus and ferry. On the 15th (Sun), wrap the sightseeing up by early afternoon so you can drive to Panama City.

Things to do in Isla Taboga

Nature Parks Historic Sites
Find places to stay Mar 14 — 15:
Highlights from your plan
Taboga Island Beaches ©
Taboga Island Beaches
Iglesia de San Pedro ©
Iglesia de San Pedro

10
nights
Panama City

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Panama City is known for historic sites, shopping, museums, nature, and nightlife. Your plan includes some of its best attractions: make a trip to Panama Canal, get to know the fascinating history of Casco Viejo, explore the wealth of natural beauty at Metropolitan National Park, and browse the different shops at Albrook Mall.

For ratings, maps, traveler tips, and other tourist information, go to the Panama City online trip itinerary planner .

You can drive from Isla Taboga to Panama City in 1.5 hours. In March, daily temperatures in Panama City can reach 90°F, while at night they dip to 76°F. Finish up your sightseeing early on the 25th (Wed) so you can catch the ferry to Contadora Island.

Things to do in Panama City

Parks Historic Sites Outdoors

Side Trip

Isla Santa Catalina
Find places to stay Mar 15 — 25:
Highlights from your plan
Panama Canal ©
Panama Canal
Amador Causeway (Calzada de Amador) ©

2
nights
Contadora Island

Contadora Island ©
The most visited of the islands in the archipelago, Contadora Island benefits from having the area's only airport, linking it to the mainland and boosting tourism.
Kick off your visit on the 26th (Thu): enjoy the sand and surf at Playa Ejecutiva. On your second day here, kick back and relax at Playa Larga, then enjoy the sand and surf at Playa de las Suecas, and then kick back and relax at Playa Cacique.

To see ratings, maps, where to stay, and more tourist information, go to the Contadora Island trip planner .

You can ride a ferry from Panama City to Contadora Island in an hour. In March in Contadora Island, expect temperatures between 92°F during the day and 74°F at night. Wrap up your sightseeing on the 27th (Fri) early enough to travel to Darien Province.

Things to do in Contadora Island

Outdoors Beaches Parks
Find places to stay Mar 25 — 27:
Highlights from your plan
Playa Larga ©
Playa Larga
Playa Ejecutiva ©
Playa Ejecutiva
Playa de las Suecas ©
Playa de las Suecas

1
night
Darien Province

Darien Province ©
Start off your visit on the 28th (Sat): explore the wealth of natural beauty at Darien National Park.

For traveler tips, where to stay, reviews, and more tourist information, read Darien Province trip planner .

Traveling by combination of ferry and flight from Contadora Island to Darien Province takes 4.5 hours. Alternatively, you can do a combination of ferry, bus, and flight; or do a combination of ferry and bus. Finish your sightseeing early on the 28th (Sat) to allow enough time to fly to San Blas Islands.

Things to do in Darien Province

Nature Parks
Find places to stay Mar 27 — 28:
Highlights from your plan
Darien National Park ©
Darien National Park

3
nights
San Blas Islands

San Blas Islands ©
San Blas Islands represent the offshore area of the indigenous province of Guna Yala.
On the 29th (Sun), head off the coast to Isla Perro. On the 30th (Mon), you'll have a packed day of sightseeing: step off the mainland to explore Isla Chichime.

To find ratings, reviews, maps, and more tourist information, read San Blas Islands trip planning website .

Getting from Darien Province to San Blas Islands by flight takes about 3 hours. Other options: take a bus; or do a combination of bus and ferry. In March, daytime highs in San Blas Islands are 92°F, while nighttime lows are 74°F. You will leave for home on the 31st (Tue).

Things to do in San Blas Islands

Nature Parks Outdoors
Find places to stay Mar 28 — 31:
Highlights from your plan
Isla Perro ©
Isla Perro

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