19 days in South America Itinerary

19 days in South America Itinerary

Created using Inspirock South America vacation maker

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Route & dates

19 days in South America Itinerary

Start: Birmingham, United Kingdom
foot + Fly:  18​h 15​min
1
Cartagena, Colombia
— 2 nights
Fly:  3​h 15​min
2
San Andres Island, Colombia
— 1 night
Fly:  7​h 15​min
3
Cusco, Peru
— 1 night
Fly:  1​h 30​min
4
Arequipa, Peru
— 1 night
Fly:  3​h 45​min
5
La Paz, Bolivia
— 1 night
Fly + taxi:  3​h 45​min
6
Uyuni, Bolivia
— 1 night
Drive:  11​h 15​min
7
San Pedro de Atacama, Chile
— 2 nights
shuttle + Fly:  6​h 15​min
8
Mendoza, Argentina
— 2 nights
Fly:  6​h 45​min
9
San Carlos de Bariloche, Argentina
— 2 nights
Fly:  10​h
10
Sao Paulo, Brazil
— 2 nights
+3
Fly + train + subway + train:  18​h
End: Birmingham, United Kingdom

2
nights
Cartagena, Colombia

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
On the 9th (Thu), see the interesting displays at Caribe Jewelry Museum & Factory, make a trip to Torre del Reloj, take in the architecture and atmosphere at Sanctuary of Saint Peter Claver, then steep yourself in history at Plaza Santo Domingo, then make a trip to Plaza Bolivar, and finally take in the spiritual surroundings of Convent of Santa Cruz de la Popa. On the 10th (Fri), you'll have a packed day of sightseeing: don't miss a visit to La Popa Monastery, then discover the deep blue sea with a scuba or snorkeling tour, and then take in the local highlights with Walking tours.

Make your Cartagena itinerary with Inspirock to find out what to see and where to go.

Birmingham, UK to Cartagena is an approximately 18.5-hour combination of car and flight. The time zone difference when traveling from Birmingham to Cartagena is minus 5 hours. Prepare for much hotter weather when traveling from Birmingham in April: high temperatures in Cartagena hover around 38°C and lows are around 30°C. Wrap up your sightseeing on the 10th (Fri) to allow time to travel to San Andres Island.

Things to do in Cartagena

Tours Outdoors Wildlife
Find places to stay Apr 8 — 10:
Highlights from your plan
Scuba & Snorkeling
Walking tours
Caribe Jewelry Museum & Factory ©
Caribe Jewelry Museum & Factory

1
night
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
Kick off your visit on the 11th (Sat): identify plant and animal life at West View, make a trip to Rocky Cay, and then identify plant and animal life at Cayo El Acuario.

To see photos, more things to do, reviews, and other tourist information, read our San Andres Island trip site .

You can fly from Cartagena to San Andres Island in 3.5 hours. April in San Andres Island sees daily highs of 36°C and lows of 30°C at night. Wrap up your sightseeing on the 11th (Sat) to allow time to travel to Cusco.

Things to do in San Andres Island

Parks Wildlife
Find places to stay Apr 10 — 11:
Highlights from your plan
Cayo El Acuario ©
Cayo El Acuario
Rocky Cay ©
Rocky Cay

1
night
Cusco, Peru

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Start off your visit on the 12th (Sun): take a stroll through San Blas and then indulge in some personalized pampering at some of the best spas. On your second day here, take a pleasant ride with a tour on horseback, make a trip to Pisac, and then delve into the distant past at Tambomachay.

To see reviews, photos, and more tourist information, use the Cusco trip planner .

Traveling by flight from San Andres Island to Cusco takes 7.5 hours. Traveling from San Andres Island in April, you will find days in Cusco are slightly colder (23°C), and nights are colder (7°C). Finish up your sightseeing early on the 13th (Mon) so you can travel to Arequipa.

Things to do in Cusco

Spas Outdoors Tours

Side Trip

Pisac
Find places to stay Apr 11 — 13:
Highlights from your plan
Spas
Horseback Riding Tours
Pisac ©
Pisac

1
night
Arequipa, Peru

Arequipa ©
In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Start off your visit on the 14th (Tue): get to know the fascinating history of Iglesia de la Compania de Jesus, contemplate the long history of Historic Centre of Arequipa, get engrossed in the history at Museo Santuarios Andinos, then don't miss a visit to Plaza de Armas, then steep yourself in history at Yanahuara, and finally examine the collection at Museo de la Catedral de Arequipa.

To see where to stay, ratings, maps, and other tourist information, read our Arequipa travel planner .

Traveling by flight from Cusco to Arequipa takes 1.5 hours. Alternatively, you can drive; or take a bus. Traveling from Cusco in April, Arequipa is somewhat warmer at night with lows of 11°C. Finish your sightseeing early on the 14th (Tue) so you can travel to La Paz.

Things to do in Arequipa

Historic Sites Museums Neighborhoods
Find places to stay Apr 13 — 14:
Highlights from your plan
Historic Centre of Arequipa ©
Historic Centre of Arequipa
Museo de la Catedral de Arequipa ©
Museo de la Catedral de Arequipa
Iglesia de la Compania de Jesus ©
Iglesia de la Compania de Jesus

1
night
La Paz, Bolivia

Take a moment to catch your breath as you commence your holiday in La Paz.
On the 15th (Wed), push the limits with an extreme tour, don't miss a visit to Mi Teleferico, and then take in the local highlights with Walking tours.

To find traveler tips, more things to do, maps, and tourist information, read La Paz trip website .

Traveling by flight from Arequipa to La Paz takes 4 hours. Alternatively, you can drive; or do a combination of flight and bus. You'll lose 1 hour traveling from Arequipa to La Paz due to the time zone difference. Plan for little chillier temperatures traveling from Arequipa in April, with highs in La Paz at 17°C and lows at 1°C. Cap off your sightseeing on the 15th (Wed) early enough to travel to Uyuni.

Things to do in La Paz

Tours Outdoors
Find places to stay Apr 14 — 15:
Highlights from your plan
Adrenaline & Extreme Tours
Walking tours
Mi Teleferico ©
Mi Teleferico

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Kick off your visit on the 16th (Thu): head off the coast to Isla Incahuasi and then explore the striking landscape at Salar de Uyuni.

To see maps, traveler tips, where to stay, and other tourist information, refer to the Uyuni travel planner.

You can do a combination of flight and taxi from La Paz to Uyuni in 4 hours. Other options are to drive; or do a combination of bus and taxi. When traveling from La Paz in April, plan for little chillier days and somewhat warmer nights in Uyuni: temperatures range from 10°C by day to 9°C at night. Wrap up your sightseeing on the 16th (Thu) to allow time to travel to San Pedro de Atacama.

Things to do in Uyuni

Nature Parks
Find places to stay Apr 15 — 16:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi

2
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Step off the beaten path and head to Salar de Tara and Piedras Rojas. There's much more to do: explore the activities along Tebinquinche Lake, don't miss a visit to Mirador de Kari, Piedra del Coyote, identify plant and animal life at Valle Arcoiris, and explore the ancient world of Pukara de Quitor.

To see more things to do, maps, and other tourist information, refer to the San Pedro de Atacama trip planner .

Getting from Uyuni to San Pedro de Atacama by combination of car and bus takes about 11.5 hours. Other options: drive; or do a combination of car, train, and bus. When traveling from Uyuni in April, plan for warmer days in San Pedro de Atacama, with highs around 28°C, while nights are little chillier with lows around 4°C. Finish your sightseeing early on the 19th (Sun) to allow enough time to travel to Mendoza.

Things to do in San Pedro de Atacama

Parks Nature Wildlife
Find places to stay Apr 17 — 19:
Highlights from your plan
Salar de Tara ©
Salar de Tara
Valle Arcoiris ©
Valle Arcoiris
Museo del Meteorito ©
Museo del Meteorito

2
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Kick off your visit on the 20th (Mon): learn about winemaking at Bodega Roberto Bonfanti, learn about winemaking at Casa El Enemigo, then indulge in some culinary diversions at a local gastronomic tour, and finally take some stellar pictures from Cerro de la Gloria. Keep things going the next day: let the river carry you with a rafting and tubing tour and then admire the engineering at Potrerillos Dam.

To see maps, where to stay, and more tourist information, go to the Mendoza journey planner.

You can do a combination of shuttle and flight from San Pedro de Atacama to Mendoza in 6.5 hours. Other options are to drive; or take a bus. Traveling from San Pedro de Atacama to Mendoza, you'll lose 1 hour due to the time zone difference. Traveling from San Pedro de Atacama in April, expect somewhat warmer with lows of 13°C in Mendoza. Cap off your sightseeing on the 21st (Tue) early enough to travel to San Carlos de Bariloche.

Things to do in Mendoza

Tours Outdoors Adventure

Side Trip

Casa El Enemigo
Find places to stay Apr 19 — 21:
Highlights from your plan
Bodega Roberto Bonfanti ©
Bodega Roberto Bonfanti
Casa El Enemigo ©
Casa El Enemigo
Potrerillos Dam ©
Potrerillos Dam

2
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Kick off your visit on the 22nd (Wed): enjoy breathtaking views from Parque Nacional Nahuel Huapi, walk around Parque Nahuelito, and then get impressive views of Cerro Tronador. Here are some ideas for day two: take in the dramatic scenery at Puerto Blest y Cascada de los Cantaro, then step off the mainland to explore Isla Victoria, and then surround yourself with nature on a nature and wildlife tour.

Inspirock's itinerary builder makes planning a San Carlos de Bariloche trip simple and quick.

You can fly from Mendoza to San Carlos de Bariloche in 7 hours. Other options are to drive; or take a bus. Prepare for little chillier weather when traveling from Mendoza in April: high temperatures in San Carlos de Bariloche hover around 17°C and lows are around 2°C. Wrap up your sightseeing on the 23rd (Thu) to allow time to travel to Sao Paulo.

Things to do in San Carlos de Bariloche

Parks Nature Wildlife
Find places to stay Apr 21 — 23:
Highlights from your plan
Ventisquero Negro ©
Ventisquero Negro
Puerto Blest y Cascada de los Cantaro ©
Parque Nahuelito ©
Parque Nahuelito

2
nights
Sao Paulo, Brazil

Sao Paulo ©
Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
On the 24th (Fri), engage your brain at Catavento Cultural e Educacional and then examine the collection at Museu da Lingua Portuguesa. Here are some ideas for day two: pause for some serene contemplation at São Paulo Cathedral, contemplate the long history of Mosteiro De Sao Bento, then admire the masterpieces at Museu de Arte de Sao Paulo Assis Chateaubriand - MASP, then take a stroll through Jardins District, and finally get engrossed in the history at Museu do Som e Imagem - MIS.

For traveler tips, maps, photos, and more tourist information, refer to the Sao Paulo vacation builder website .

Fly from San Carlos de Bariloche to Sao Paulo in 10 hours. Alternatively, you can do a combination of flight and bus; or drive. While traveling from San Carlos de Bariloche, expect a bit warmer days and much hotter nights in Sao Paulo, ranging from highs of 30°C to lows of 20°C. Finish your sightseeing early on the 26th (Sun) so you can travel back home.

Things to do in Sao Paulo

Museums Childrens Museums Historic Sites
Find places to stay Apr 23 — 26:
Highlights from your plan
Catavento Cultural e Educacional ©
Catavento Cultural e Educacional
Museu do Som e Imagem - MIS ©
Museu do Som e Imagem - MIS
Jardins District ©
Jardins District

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